Aldactone is used for:

Treating swelling and fluid retention inpatients with congestiveheart failure, cirrhosis, or kidney problems (nephrotic syndrome). Itis also used for treatment of high blood pressure. It may also be usedto treat or prevent low blood potassium. It may also be used to treatexcess secretion of the hormone aldosterone by the adrenal gland.

Aldactone is a potassium-sparing diuretic. It works by blocking thehormone aldosterone, causing the kidney to eliminate excess water, savepotassium, and lower blood pressure.

Do NOT use Aldactone if:

• you are allergic to any ingredient in Aldactone
• you are unable to urinate, have severe kidney problems, or have high blood potassium levels
• you are taking a potassium supplement,another potassium-sparing diuretic (eg, amiloride, triamterene), oranother aldosterone-blocker (eg, eplerenone)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Aldactone :

Some medical conditions may interact with Aldactone . Tell yourdoctor or pharmacist if you have any medical conditions, especially ifany of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have high acidity in your bodyfluids; low sodium levels in your blood; liver, heart, or lung disease;diabetes; or high urea or nitrogen in your blood
• if you have menstrual disease

Some MEDICINES MAY INTERACT with Aldactone . Tell your health careprovider if you are taking any other medicines, especially any of thefollowing:

• Corticosteroids (eg, prednisone) or ACTH because low blood electrolyte levels may occur
• Barbiturates (eg, phenobarbital) or narcotics (eg, morphine) because dizziness upon standing may occur
• Angiotensin-converting enzyme (ACE)inhibitors (eg, enalapril), angiotensin II receptor antagonists (eg,valsartan), cyclosporine, macrolide immunosuppressives (eg,tacrolimus), other potassium sparing diuretics (eg, amiloride,triamterene), other aldosterone-blockers (eg, eplerenone), or potassiumsupplements because high blood potassium levels may occur (eg,listlessness, confusion, abnormal skin sensations of the arms and legs,heaviness of limbs, slowed heart rate, irregular heart rhythm,potentially life-threatening slow or irregular heartbeat)
• Nonsteroidal anti-inflammatory drugs(NSAIDs) (eg, indomethacin) because they may decrease Aldactone 'seffectiveness and increase the risk of kidney problems and high bloodpotassium
• Digoxin, digitoxin, lithium,nondepolarizing muscle relaxants (eg, tubocurarine), or quinidinebecause the risk of their side effects and toxicity may be increased byAldactone
• Pressor amines (eg, norepinephrine) because their effectiveness may be decreased by Aldactone

This may not be a complete list of all interactions that may occur.Ask your health care provider if Aldactone may interact with othermedicines that you take. Check with your health care provider beforeyou start, stop, or change the dose of any medicine.

Possible side effects of Aldactone :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abdominal cramping; change in sexual ability; clumsiness; confusion; diarrhea; dizziness; drowsiness; headache; frequent urination; nausea; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swellingof the mouth, face, lips, or tongue); breast tenderness; deepening ofvoice; dry mouth; enlarged breasts in men; excessive thirst; irregularor lack of menstrual periods; skin rash; slow, irregular, or fastheartbeat; ulcers; unusual muscle weakness; unusual tiredness.

General information:

• If you have any questions about Aldactone , please talk with your doctor, pharmacist, or other health care provider.
• Aldactone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is summary only. It does not contain allinformation about Aldactone . If you have questions about the medicineyou are taking or would like more information, check with your doctor,pharmacist, or other healthcare provider.